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| Wed | May 13 | TC | BMO Centre Full Field | 20:30 | Upper Canada Rebellion | | Brazukas FC B |
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| Wed | May 13 | 1 | Hellenic Comm. Centre | 20:30 | Brazukas FC A | | London Scottish FC |
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| Thu | May 14 | 2 | Exeter Comm. Park | 20:30 | St Columban SC | | London Dinamo FC B |
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| Thu | May 14 | East 3 | Portuguese Club - London | 20:30 | London Dinamo FC C | | German Canadian FC B |
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| Thu | May 14 | 1 | Taxandria Soccer Complex #1 | 19:00 | Taxandria SC A | | Woodstock FC B |
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| Fri | May 15 | P | Cowan - Guarantee | 20:00 | Woodstock FC A | | London Olympians |
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| Fri | May 15 | P | Henk Van Dyk Stadium | 20:30 | Strathroy United FC A | | London Thunder FC |
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| Fri | May 15 | 1 | Keil Drive 1 | 19:30 | Chatham SC | | London Athletic Canadian FC |
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| Fri | May 15 | 2 | McLaughlin | 20:00 | Norfolk Athletics | | German Canadian FC A |
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| Fri | May 15 | 1 | Norm Perry Park Turf | 20:30 | Sarnia FC A | | St Thomas SC |
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| Fri | May 15 | 2 | Tillsonburg Park 1 | 20:30 | Tillsonburg FC | | Taxandria SC B |
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| Sat | May 16 | 2 | Henk Van Dyk Stadium | 18:30 | Strathroy United FC B | | Woodstock FC C |
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| Sat | May 16 | P | St. Sava Church | 18:00 | London Serbians SC | | Jagiellonia London |
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| Sun | May 17 | P | 1Password - St Thomas 11v11 A | 19:30 | London Dinamo FC A | | London St Thomas Croatia SC |
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| Sun | May 17 | West 3 | Lucan Soccer Complex Field 3 | 18:00 | Lucan SC | | Chatham SC B |
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| Sun | May 17 | West 3 | Oak Park | 16:00 | Oakridge Blast | | Sarnia FC B |
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| Sun | May 17 | East 3 | Thames Centre ORC #2 | 20:00 | Upper Canada Rebellion | | Ingersoll Flyers |
