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| Wed | May 7 | 3 | Polish Canadian Rec Centre 1 | 18:30 | Brazukas FC B | 6 - 1 | London Serbs B |
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| Thu | May 8 | 3 | St. Clair College - Thames Campus | 18:30 | Chatham Soccer U23 | 1 - 4 | Oakridge Blast |
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| Fri | May 9 | 2 | Exeter Comm. Park | 20:30 | St Columban A | 0 - 3 | St Columban Celtic Crusaders |
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| Fri | May 9 | 1 | McLaughlin | 20:00 | Norfolk Athletics | 1 - 1 | Woodstock Stallions B |
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| Fri | May 9 | 2 | Norm Perry Park Turf | 20:00 | Sarnia FC A | 2 - 0 | Woodstock Stallions C |
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| Sat | May 10 | 1 | Citywide Field #2 | 17:30 | LACFC | 0 - 1 | Taxandria First |
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| Sat | May 10 | 3 | Germain Park 4 | 17:00 | Sarnia FC B | 1 - 0 | Ingersoll Flyers |
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| Sat | May 10 | 2 | Polish Canadian Rec Centre 1 | 10:00 | Brazukas FC A | 4 - 2 | St Marys Juggernauts |
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| Sat | May 10 | 1 | Scotia Park | 14:00 | London Scottish | 2 - 0 | Tillsonburg |
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| Sun | May 11 | P | 1Password Turf - St Thomas | 20:30 | London Dinamo FC A | 7 - 0 | Taxandria Premier |
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| Sun | May 11 | 3 | Athletic Park 1 | 16:00 | St Thomas | 4 - 0 | Norfolk Royals U23 |
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| Sun | May 11 | P | Croatia Field #1 - London | 18:00 | Croatia | 5 - 0 | London Serbs A |
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| Sun | May 11 | 2 | German Canadian FC Stadium Field | 20:00 | GCFC Second | 1 - 1 | Strathroy United FC B |
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| Sun | May 11 | P | Hellenic Comm. Centre | 19:00 | London Olympians | 3 - 1 | Woodstock Stallions A |
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| Sun | May 11 | P | Polish Canadian Rec Centre 1 | 17:00 | Jagiellonia | 2 - 2 | London Thunder |
